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Workplaces that involve contact with blood or other potentially infectious materials must follow strict safety procedures. Safe work practices reduce the risk of exposure to bloodborne pathogens (BBPs) such as HIV, Hepatitis B, and Hepatitis C. When combined with engineering controls, personal protective equipment (PPE), and proper training, these practices create a safer environment for employees and the individuals they serve.
Safe work practices are procedures and behaviors designed to reduce the likelihood of exposure to blood and bodily fluids. Unlike engineering controls, which physically isolate hazards, safe work practices focus on how tasks are performed.
These include proper hand hygiene, correct use of PPE, safe handling of sharps, surface disinfection, and immediate reporting of exposure incidents. Safe work practices are part of OSHA’s Bloodborne Pathogens Standard and are required in any setting where occupational exposure may occur.
Safe work practices are essential because even small mistakes can result in serious health risks. A single needlestick injury or improper cleanup of contaminated surfaces can expose workers to infectious diseases.
Consistent adherence to safe procedures:
Prevention is always more effective and less costly than responding to an exposure incident.
Workers should follow these core practices to stay safe:

Universal Precautions mean treating all blood and certain bodily fluids as potentially infectious, regardless of the perceived risk.
This approach eliminates guesswork. Instead of deciding whether a person is infected, workers assume the possibility of infection and follow protective procedures at all times. Universal Precautions form the backbone of safe work practices in healthcare, laboratories, childcare, and public safety roles.
PPE provides a barrier between workers and infectious materials. Appropriate PPE may include:
Employees must wear PPE whenever exposure is possible, remove and dispose of PPE properly, avoid touching surfaces with contaminated gloves, and replace damaged PPE immediately PPE should never replace safe work practices. It is part of a complete protection strategy.
Hand hygiene is one of the most effective infection prevention measures. Workers should:
Proper decontamination also includes cleaning reusable equipment and following approved disinfectant procedures.
Sharps injuries are one of the most common sources of occupational exposure. Safe practices include:
Immediate and proper disposal significantly reduces the risk of needlestick injuries.
Contaminated surfaces can spread infection if not properly cleaned. Safe cleaning procedures include:
Routine cleaning reduces cross-contamination and protects both workers and clients.
An exposure control plan is a written document required by the Occupational Safety and Health Administration (OSHA) under the Bloodborne Pathogens Standard. It explains how an organization will eliminate or minimize employee exposure to human blood, body fluids, and other potentially infectious materials.
A comprehensive Bloodborne Pathogens Exposure Control Plan identifies job classifications at risk, outlines the use of work practice controls and administrative controls, and details procedures for handling and disposing of contaminated materials. It also addresses the use of safer medical devices, including needleless devices and self-sheathing needles, proper placement of sharps disposal containers, and safe management of biohazardous waste.
The plan must include access to Hepatitis B vaccination, procedures for post-exposure evaluation, and documentation practices such as maintaining a sharps injury log. OSHA requires employers to review and update the plan annually to maintain compliance and strengthen overall Workplace Safety.
Avoid these common mistakes:
Unsafe shortcuts can lead to serious consequences.
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In schools, childcare centers, and care facilities, additional caution is required. Children and vulnerable populations may not understand infection risks. Staff should:
Consistent safety protocols protect both caregivers and those in their care.
OSHA requires initial and annual training for employees with occupational exposure to bloodborne pathogens. Training must include:
ATAC offers online Bloodborne Pathogens training that helps organizations stay compliant with OSHA requirements while reinforcing safe work practices. Regular refresher training ensures employees remain confident and prepared.
If a needlestick puncture, mucous membrane contact, or other exposure occurs, immediate action is essential. Employees must follow established Emergency Procedures and complete an Exposure Incident Report as soon as possible. The affected area should be washed or flushed immediately, followed by a prompt post-exposure evaluation. Employers are required to provide access to medical consultation, appropriate post-exposure procedures, and consideration of Post-exposure prophylaxis when indicated. Follow-up may include laboratory tests, such as HCV RNA testing, and documentation in the organization’s sharps injury log to monitor trends and prevent future incidents.
Not all exposures can be prevented, but most are avoidable when proper safe work practices are followed. Consistent use of PPE, adherence to Universal Precautions, and proper sharps handling significantly reduce risk. Ongoing training further lowers the chance of workplace exposure.
OSHA requires annual refresher training for employees with occupational exposure. Additional training may be necessary when procedures change, new equipment is introduced, or after an exposure incident. Regular retraining reinforces safe habits and maintains compliance.
Engineering controls are physical or mechanical devices that isolate or remove a hazard from the workplace, while safe work practices are procedures and behaviors that reduce exposure by changing how tasks are performed. OSHA’s Bloodborne Pathogens Standard requires employers to implement engineering controls and safe work practices, along with PPE, to minimize occupational exposure.
Healthcare workers, Laboratory personnel, and staff in a Clinical Laboratory face increased risk of bloodborne infections and bloodborne diseases because they frequently handle human blood, body fluids, and potentially infectious materials. Protection begins with strict adherence to standard precautions, treating all blood and body fluids as potentially infectious. Employees are required to wear appropriate personal protective clothing, including gloves and laboratory coats, and may use Biological Safety Cabinets when working with high-risk specimens. Employers must implement Sharps injury protection strategies and ensure proper disposal in labeled sharps containers displaying the Biohazard symbol.
Employers are required to offer the Hepatitis B vaccination at no cost to employees who have occupational exposure risk. The Hepatitis B virus (HBV) can survive outside the body for extended periods, making vaccination one of the most effective preventive measures in a comprehensive Bloodborne Pathogens Program.


